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| | Name | daf-15 |
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| Organism | Caenorhabditis elegans |
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| Aging Phenotype | Life-span extension |
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| Allele Type | Recessive |
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| Strain | N2 |
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| Description | Mutations in daf-15 increase life span by15-30% (Jia et al., 2004). Life span extension is dependent on the Daf-16 transcription factor. |
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| Gene Function | TOR regulator protein |
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| Other Phenotypes | daf-15 mutants are dauer constitutive (Jia et al., 2004). |
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| Homologs | N/A
N/A
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| Primary Reference | Jia, K., Chen, D., and Riddle, D. L. (2004). The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development. [Abstract]
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| Other References | |
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| Relevant Links | WormBase: http://www.wormbase.org/db/gene/gene?name=daf-15
LocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=267109
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| Keywords | Caenorhabditis, elegans, worm, insulin, signaling, transcription factor, dauer, metabolism, caloric restriction, nutrient |
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