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| | Name | bsk |
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| Organism | Drosophila melanogaster |
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| Aging Phenotype | Correlation |
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| Allele Type | N/A |
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| Strain | OreR, ry506, armGAL4, elavGAL4 |
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| Description | Increased JNK pathway activity correlates with increased life-span and enhanced resistance to oxidative stress in flies (Wang et al., 2003).
See database entries puc, hep, and hsp68. |
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| Gene Function | Stress activated protein kinase. MAP kinase. |
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| Other Phenotypes | Activation of JNK induces oxidative stress resistance. |
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| Homologs | |
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| Primary Reference | Wang, M. C., D. Bohmann and H. Jasper, 2003 JNK Signaling Confers Tolerance to Oxidative Stress and Extends Lifespan in Drosophila. Dev Cell 5: 811-816. [Abstract]
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| Other References | |
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| Relevant Links | FlyBase: http://flybase.bio.indiana.edu/.bin/fbidq.html?FBgn0000229
LocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=44801
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| Keywords | stress activated protein kinase, oxidative stress, fly |
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