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| | Name | BCY1 |
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| Organism | Saccharomyces cerevisiae (replicative) |
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| Aging Phenotype | Shortened life-span |
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| Allele Type | Deletion |
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| Strain | SP1 |
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| Description | Deletion of BCY1 results in a shortened life-span (Sun et al., 1994). |
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| Gene Function | Regulatory subunit of protein kinase A (PKA) |
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| Other Phenotypes | Mutation of BCY1 results in increased PKA activity. |
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| Homologs | S.p. CGS1
R.n. PRKAR2A, PRKAR1B, PRKAR1A ...
H.s. PRKAR2A, PRKAR2B, PRKAR1A ...
C.e. KIN-2
M.m. PRKAR2A, PRKAR1B ...
D.m. PKA-R1
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| Primary Reference | Sun, J., Kale, S. P., Childress, A. M., Pinswasdi, C., and Jazwinski, S. M. (1994). Divergent roles of RAS1 and RAS2 in yeast longevity. J Biol Chem 269, 18638-45. [Abstract]
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| Other References | |
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| Relevant Links | SGD: http://genome-www4.stanford.edu/cgi-bin/SGD/locus.pl?locus=bcy1
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| Keywords | yeast, Saccharomyces cerevisiae, cAMP, caloric restriction, metabolism, replicative senescence |
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