|
| | Name | daf-28 |
|---|
| Organism | Caenorhabditis elegans |
|---|
| Aging Phenotype | Life-span extension |
|---|
| Allele Type | Semi-dominant |
|---|
| Strain | Bristol N2 |
|---|
| Description | Semi-dominant mutation increases life span by 10-15% (Malone et al., 1996). |
|---|
| Gene Function | Not cloned. |
|---|
| Other Phenotypes | daf-28 mutant is dauer constitutive (Malone and Thomas, 1994). |
|---|
| Homologs | N/A
|
|---|
| Primary Reference | Malone, E. A., Inoue, T., and Thomas, J. H. (1996). Genetic analysis of the roles of daf-28 and age-1 in regulating Caenorhabditis elegans dauer formation. Genetics 143, 1193-205. [Abstract]
|
|---|
| Other References | Malone, E. A., and Thomas, J. H. (1994). A screen for nonconditional dauer-constitutive mutations in Caenorhabditis elegans. Genetics 136, 879-86. [Abstract]
|
|---|
| Relevant Links | WormBase: http://www.wormbase.org/perl/ace/elegans/gene/locus?name=daf-28
LocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=267111
|
|---|
| Keywords | dauer, Caenorhabditis, elegans, worm |
|---|
|