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| | Name | age-2 |
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| Organism | Caenorhabditis elegans |
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| Aging Phenotype | Life-span extension |
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| Allele Type | Recessive |
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| Strain | Bristol N2 |
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| Description | Mutation increases life-span by approximately 15-20% (Yang and Wilson 1999). An age-1 age-2 double mutant strain lives longer than either single mutant and exhibits a longer life-span at 25C than at 20C. |
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| Gene Function | Unknown. Gene has not been mapped or cloned. |
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| Other Phenotypes | Mutant exhibits normal motility and reduced fertility (Yang and Wilson, 1999). |
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| Homologs | N/A
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| Primary Reference | Yang, Y., and Wilson, D. L. (1999). Characterization of a life-extending mutation in age-2, a new aging gene in Caenorhabditis elegans. J Gerontol A Biol Sci Med Sci 54, B137-42. [Abstract]
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| Other References | None.
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| Relevant Links | WormBase: http://www.wormbase.org/perl/ace/elegans/gene/locus?name=age-2
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| Keywords | Caenorhabditis, elegans, worm |
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