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| | Name | CYT1 |
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| Organism | Saccharomyces cerevisiae (replicative) |
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| Aging Phenotype | No effect on life-span |
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| Allele Type | Deletion |
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| Strain | PSY316 |
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| Description | Deletion of CYT1 has no effect on life-span, but prevents life-span extension by overexpression of HAP4 (Lin et al., 2002). |
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| Gene Function | Cytochrome c1. |
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| Other Phenotypes | CYT1 is required for respiration in yeast. |
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| Homologs | M.m. CYC1
H.s. CYC1
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| Primary Reference | Lin, S. J., Kaeberlein, M., Andalis, A. A., Sturtz, L. A., Defossez, P. A., Culotta, V. C., Fink, G. R., and Guarente, L. (2002). Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 418, 344-8. [Abstract]
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| Other References | |
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| Relevant Links | SGD: http://genome-www4.stanford.edu/cgi-bin/SGD/locus.pl?locus=CYT1
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| Keywords | oxygen, oxidative stress, yeast, replicative senescence, fermentation, respiration, mitochondria, electron transport, caloric restriction |
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