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| | Name | che-11 |
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| Organism | Caenorhabditis elegans |
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| Aging Phenotype | Life-span extension |
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| Allele Type | Recessive |
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| Strain | Bristol N2 |
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| Description | Loss of function increases life-span up to 40% (Apfeld and Kenyon, 1999). |
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| Gene Function | Not cloned. |
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| Other Phenotypes | Mutants are dye filling defective, defective in osmotic avoidance and dauer formation, and have irregular amphid cilia (Perkins et al., 1988) |
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| Homologs | N/A
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| Primary Reference | Apfeld, J., and Kenyon, C. (1999). Regulation of lifespan by sensory perception in Caenorhabditis elegans. Nature 402, 804-9. [Abstract]
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| Other References | Perkins, L. A., Hedgecock, E. M., Thomson, J. N., and Culotti, J. G. (1986). Mutant sensory cilia in the nematode Caenorhabditis elegans. Developmental Biology 117, 456-487. [Abstract]
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| Relevant Links | WormBase:
http://www.wormbase.org/db/gene/locus?name=che-11;class=Locus
LocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=179666
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| Keywords | Caenorhabditis, elegans, worm, neurons, dauer |
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