| Faculty Member |
Affiliation |
Research Interests |
| Peter S. Rabinovitch |
Director, Pathology |
Cell cycle, cell proliferation and genetic instability in aging
and early neoplasia
|
| George Martin |
Associate Director, Pathology & Genetics |
Cellular aging, Alzheimer's Disease |
| Mark A. Bothwell |
Physiology and Biophysics |
Role of neurotrophic factors in neural development, degeneration and regeneration
|
| Peter Byers |
Pathology |
The characterization of mutations in type I collagen genes (COL1A1
and COL1A2) that give rise to forms of osteogenesis imperfecta (OI)
and other disorders
|
| Kevin Conley |
Psychiatry & Behavioral Sciences |
The decline in mitochondrial function with age under resting (state 4)
and exercising or maximal (state 3) conditions
|
| Dave Cook |
Pharmacology |
The maturation kinetics, trafficking, and long-term accumulation of
intracellular Amyloid-beta in human NT2N neurons
|
| Christine M. Disteche |
Pathology |
Gene inactivation/reactivation, structure and
function of the X and Y chromosomes in mammals
|
| Dave Eaton |
Environmental Health |
The biochemical and molecular basis for species, interindividual and aging
differences in response to chemical carcinogens and aging.
|
| Stan Fields |
Genome Sciences & Medicine |
Simple eukaryote Saccharomyces cerevisiae as a model to analyze proteins
and processes implicated in human diseases
|
| Clement Furlong |
Medical Genetics |
Interplay of genetics and the environment, including risk reduction through
bioremediation, and the effect of polymorphisms of antioxidant
enzymes, especially paraoxonase, on age-related diseases
|
| Dan Gottschling |
FHCRC |
|
| Terrance J. Kavanagh |
Environmental Health |
Oxygen free radicals and glutathione metabolism in environmental disease
and aging
|
| Brian Kennedy |
Biochemistry |
|
| Mary-Claire King |
Medicine, Genome Sciences |
The genetics of complex, common human conditions, including Breast and
ovarian cancer and inherited deafness.
|
| Warren Ladiges |
Comparative Medicine |
|
| Albert La Spada |
Neurobiology and Behavioral Sciences |
|
| Renee C. LeBoeuf |
Pathobiology |
Understanding the molecular mechanisms causing
Alzheimer�s Disease (AD)
|
| Lawrence A. Loeb |
Pathology |
DNA replication fidelity, aging and cancer
|
| Mike MacCoss |
Genome Sciences |
|
| Nancy Maizels |
Immunology |
DNA recombination and repair in mammalian cells: how repair and recombination
enzymes (including WRN and the RecQ family of helicases) function to maintain
genomic stability.
|
| Raymond J. Monnat |
Pathology |
Mutagenesis, oxygen free radicals, aging and cancer |
| Debbie Nickerson |
Molecular Biotechnology |
Analysis of SNPs and other human polymorphisms. Developing approaches to
improve the sensitivity, accuracy, and speed of identifying and typing these
potentially functional genomic variations.
|
| Thomas Norwood |
Pathology |
|
| Junko Oshima |
Pathology |
Elucidation of the pathogenesis of human progerias (diseases of premature
aging), Werner's and Hutchinson Gilford Syndromes.
|
| Leo Pallanck |
Genetics |
|
| Elaine R. Peskind |
Psychiatry and Behavioral Sciences |
Hypothalamic-pituitary-adrenal axis in aging and
Alzheimer's Disease (AD)
|
| Steven Plymate |
Medicine |
Insulin-like growth factor (IGF) receptor, senescence-associated genes,
and androgen in prostate cancer
|
| Brad Preston |
Pathology |
|
| Le Bris S. Quinn |
Medicine |
Cellular and molecular endocrinology of skeletal
muscle trophic factors
|
| Murray A. Raskind |
Psychiatry and Behavioral Sciences |
Studies of Alzheimer's disease, aging, depression, and
noncognitive behavioral problems in dementia
|
| May J. Reed |
Gerontology and Geriatric Medicine |
Angiogenesis in Aging
|
| Mark Roth |
Basic Sciences (FHCRC) |
Regulation of ribosome biogenesis, centromere structure and function,
autoimmune disease, and oxygen sensing
|
| Gerald D. Schellenberg |
Medicine |
Genetics of neurodegenerative diseases
|
| Karen G. Stephens |
Medical Genetics |
Genetics and pathology of inherited skin disorders and gene
mapping
|
| Daniel Storm |
Pharmacology |
Study of the hypothesis that the decline in the type I adenylyl cyclase
in the hippocampus may contribute to memory loss associated with aging.
|
| Bruce Tempel |
Otolaryngology |
|
| James Thomas |
Genome Sciences & Medicine |
|
| Richard Veith |
Psychiatric & Behavioral Sciences |
|
| Enrique C. Villacres |
Pharmacology |
Role of cAMP cascade proteins in memory, learning and
synaptic plasticity
|
| Elaine M. Wijsman |
Medical Genetics |
Genetic linkage studies, including Alzheimer's Disease |
| Norman S. Wolf |
Pathology |
Study of aging as it affects the lens epithelium and bone (osteoblasts);
the mechanism(s) and prevention of age related cellular changes
|
| Ziporah Yablonka-Reuveni |
Biological Structure |
Biology of the adult skeletal muscle stem cells (satellite cells).
|
| Zhengui Xia |
Environmental Health |
Molecular basis for free radical based neuronal cell death
|
